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DOC 0000017445
Page 157
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in human behavior. ...
Such fundamental research on mechanisms
of action and structure-activity relationships as is necessary to the
consistent productiomof such materials will be undertaken as re-
quired in addition to the practical evaluatiorTofltiem.
Compounds
from many sources will be evaluated in addition to those of special
interest to the
Several particularprojects for the coining year hav e been
discussed with the
representative and plans are
•
—
r-
—
being made to carry these out in addition to any others which may
arise during the year,
fhese particular pr ojects are as follows:
1.
To evaluate the effects of large dcses of
LSD -25 in normal human volunteers.
2,
To evaluate the threshold dose levels in
hurnans of a particular natural product to
be supplied by
t
This
*-
-
evaluation presents difficulties of a nature
which makes
it a unique problem.
3.
To evaluate in human beings a substance
which we now believe has the ability to
counteract the inebriating effects-of ethyl
alcohol.
•V#.
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