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DOC 0000190090
Page 66
66 / 396
OBJECTIVE AND DETAILS
OF
ORK:
i he elucidation
of
the
site
and mechanism or action
of
LSD
by
the
use of
isotopically tacged
molecules.
The advantages
to
the Agency where
(I)
the
data
should
greatly
facilitate
the development of
a
suitable antidote
and
block-
ing agent
tor
LSD,
(2)
identify possibilities
rcr
the design
of new
psychogenic
compounds,
and
(3)
tuncamental
knowledge
or
the psycho
-
therapeutic
action
or drugs
will
ce made available.
The
study
had
two
basic
thrusts:
the
synthesis
or
LSD
and
related compounds
by chemical
means;
and
learning
the metabolism,
site of action,
etc.,
of LSD
and
related
compounds
and,
if possible,
the chemical
alterations
of cells
in
the
central
nervous
system,
liver or
muscles
.
APPROXIMATE
TIME
SPAN
:
1953-1955
SIGNIFICANT ASPECTS:
None
indicated.
FUNDING
:
COVER MECHANISM
:
Geschickter Foundation
APPROXIMATE TOTAL :S30. 000
RESEARCH PARTICIPAN
unknown
if witting;
unknown
i f
wi tti ng
;
unknown
ir witting.
unwi tti ng
;
,
unknown
if witting,
,
unknown
if
witting;
J
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