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DAY 1 or 2: or oo rey a #4: Molecular Biology and Genomics Chairman: The genome of B. anthracis strain Ames: sequence and analysis IGR) Sequen 01 and pX02: Updaies etc.) Characezatin aL esi replication sequences DAY 2: #5: Cell Structure and Function: Chairman: ie} Genetic Control of Sporulation and Germination OR Genetc Control of Spore and Vegetative Cell Structure oe PoviewL—__] Germination genes of 8. anthracis: , Ireland, germination loci) - group, germination loci) Characteristics of the exosporium (Update: |__| Spore Structural Proteins - [OR in Topic #3] S-Layer ‘Homologous Domains of bacierial suriace proteins ee ero #6: Genetic Regulation and Pathogenesis Chairman: Plasmid and chromosomal regulation of toxin gene expression [| Identification of receptor-binding regions in PA (two groups): : (1 et al. : (2 et al. Oleomerzation.aly and cellular uptake of toxin Mechanism of anthrax toxin entry into cells (1) Characterization of the PA Channel (2) A polarized epithelial cell model for toxin entry