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DAY 1 or 2: #4: Molecular Biology and Genomics The genome of B. anthracis strain Ames: sequence and analysis IGR) Sequence anal ses of pX01 and pX02: Updates | bic.) Characerization of plasmid replication sequences DAY 2: #5: Structure and Function: Chairman: ) Genetic Control of Sporulation and Germination OR Genetc Control of Spore and Vegetative Cell Structure (Review: Germination genes of B. anthracis: ermination loci) group, germination loci) Characteristics of the exosporium (Update Spore aoe [OR in Topic #3] S-Layer ins of b j teins roup #6: Pathogenesis and Genetic Requlation Chairman: The pee perce Regulation of pagA by pagR Identification of receptor-binding regions in PA (iwo groups): (1) (2) Olgomprization ot and cellular uptake of toxin Mechanism of anthrax toxin entry into cells (1) Characterization of the PA Channel (2) A polarized epithelial cell model for toxin entry