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Approved For Release 2003/Q4¢ AE CIA-RDP96-00788R001300020001-6 ST-CS-01-169-72 July 1972 2, (U) Poisoning with piperidyl glycolates is hardly to be distinguished from LSD poisoning at the beginning, because also in the first mentioned class of materials the first psychic effects occur after 45 to 60 minutes. They consist of confusion, speech difficulty, disorientation and hallucination of optical and acoustic type. It is to be noted that in piperidyl glycolate psychosis the victim can still describe his condition relatively clearly after a dose of 0.5 to 2.0 mg. At doses of 10 mg and above, however, contact with the environment and insight into the arti- ficiality of the condition is lost. The victims react only to their hallucinations, or they present a stupor syndrome. At still higher doses (15 mg) there is generally a severe disturbance of consciousness with almost complete lack of consciousness. The effect of Ditran, for example, lasts for about 24 hours, and some- times as long as 36 hours. Other toxic phenomena are not to be anticipated at the indicated doses, -- at the most nausea and emesis. PART C - Countermeasures 1. (U) In the use of psychotropic warfare agents, the enemy sets himself the task of weakening the will and fighting capability of the opponent, or to bring about his complete inability to act or fight. For this reason, only well-timed application of pro- tective equipment and measures for guaranteeing indubitably uncon- taminated drinking water and food can afford flawless protection. This condition in this case has so much the greater significance because a timed alarm is questionable in dealing with psychotropic agents. Certain medicaments are available to the physician for the treatment of those already poisoned to offset the worst effects. As antidotes there are: (1) Azacyclonol (Frenquel) in an i.v. or oral dose of 200 mg (2) Succinic acid, infusion in a 5% phosphate buffered solution (5m1/min) (3) Tetrahydroaminacrin, 30 mg i.v. within 5 minutes (4) Chlorpromazine (Thorazine) 25 mg i.m. or oraily larger doses . 2, (U) The medicaments under one and two are indicated in poisoning with LSD, psilozine and psilocybin. The medicament under three is. to be given in poisoning with piperidyl benzilate or piperidyl glycolate. Chlorpromazine has a favorable effect on most wtiodel psychoses induced by known psychotropic warfare agents. 70 NO FOREIGN DISSEMINATION (This page is UNCLASSIFIED)