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vessels and supplies tbs oapaula for tbsss major structures, as wall aa their suppcrtlngatrcma. This definition doas not emphasize the moat important cell#j tbe fibroblasts, which show various stages of development froa the reticulum eelle to the adult fibrocytea ad also a' parallel line of.development (usually under ,r pathologic conditions) from reticulum colls to histiocytesJ The definition also does not emphasise an additional specialised ccapootat of connective tissue, the basasont mesbrane. *b» matrix of connective tissue contains s variety of socopolysaccbarldee, such aa hyaluronic acid and ohondroitln sulfate in combination with proteins. In this matrix are embedded fibers of collagen, reticulin and elastics, which ax's defined as precipitated scleroproteins • The elastics does not concern us here, but. the reticulin and collagen fibers do. The collagen fibers are polymerized polypeptides, which are oriented In linear fashion and contain a snail aami ef meop^psacchardde* T&fejetipiliBtffiMrs are really nonoriented scleroproteins vrlth nors abundant mucopolysaccharide. They any be termed precollagenous fibrils with a leas differentiated structure. 0a The important point is that both are precipitated -ef formed from the matrix. The third noncellnlar structure, besides fibers and ground substance, is the basement membrane, which is formed from reticulin fibers and condensed matrix. -- i which a tains more intensively for mucopolysaccharides than the ground substance. This condensed matrix at the basement membrane ls usually termed cementin and also fottos a binding substance between the endothelial cells In the capillary wall. Histogenesis of the Aschoff Body In pathologic response, depolymerization of the reticulin fibers and the condensed ground substance, both of which form the basement membrane of small vessels, permits hydration of the matrix, which is hydrophilic and retains water and absorbs electrolytes. At the saae time the cement substance of the capillary wall is similarly affected. The initial stage, therefore. In the O